WebApplications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin. WebFlagship Pharmaceutical APIs: Dapagliflozin & Sitagliptin & Empagliflozin & Linaglipin & Vildagliptin
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(E)-1- (3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo [4,3-a ...
WebTo a clean flask, 34.73g (R)-methyl 3- (tert-butoxycarbonylamino)-4- (2,4,5-trifluorophenyl)butyrate, 100ml toluene, 160ml water and 4.8g sodium hydroxide were added. The mixture was warmed to 60C and kept at this temperature for 3 hours. 4.73g hydrochloric acid was added dropwisely. WebThe interface composed of 3,4,5-trifluorophenyl phosphonic acid (PA) molecules … WebAug 12, 2024 · @article{Parmeggiani2024BiocatalyticRA, title={Biocatalytic retrosynthesis … golf courses near murphy nc